Thyroid-Associated Ophthalmopathy in Iranian Patients

  • Mohsen Bahmani Kashkouli Department of Medicine, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Sara Jam Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran.
  • Duman Sabzvari Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran.
  • Nooshin Ketabi Department of Medicine, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Shahrzad Azarinia Department of Medicine, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • SeyedAhmad SeyedAlinaghi Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran.
  • Alireza Mofid Department of Internal Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Keywords: Thyroid-associated ophthalmopathy, Thyroid orbitopathy, Thyroid eye disease

Abstract

We determined the frequency of clinical thyroid ophthalmopathy in Iranian patients. This cross-sectional study was performed at the Endocrinology Institute of Tehran University of Medical Sciences. All patients with documented thyroid disorders from September 2003 to July 2005 were recruited. Eye examinations included evaluation of soft tissue changes, measurement of proptosis, lid width, lagophthalmos, evaluation of eye muscle function, and determination of visual acuity. The activity of ophthalmopathy was scored according to the NOSPECS scale. Among 851 visited patients, 303 cases had thyroid eye disease (TED). The nature of the ophthalmopathy breaks down as follows: 53.4% were hypothyroid (9.3% Hashimoto disease), 5.5% euthyroid and 41.1% had Graves' disease. The prevalence of TED in males was 60% which was nearly 2 times the prevalence of TED in females. There was a significant relationship between presentation of TED and active smoking of the patients (P

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How to Cite
1.
Bahmani Kashkouli M, Jam S, Sabzvari D, Ketabi N, Azarinia S, SeyedAlinaghi S, Mofid A. Thyroid-Associated Ophthalmopathy in Iranian Patients. Acta Med Iran. 49(9):612-618.
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