Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 63 3 2025 09 23 159 164 Lina Sheehan Sheehan Rasein Department of Maternal and Neonate Nursing, Ministry of Health, Baghdad Health Directorate, Baghdad, Iraq. Salma K Jihad Department of Community Nursing, College of Nursing, University of Babylon, Babylon, Iraq. Bushra AL Rubayae Department of Obstetrics and Gynecology, College of Medicine, University of Babylon, Babylon, Iraq 2024 11 22 2024 12 03 Infertility is a difficult experience that can greatly impact a woman's mental, emotional, and thus, physical wellbeing. The study aimed to assess the infertility-related stress among women attending an infertility center and the associated socio-demographic characteristics. A cross-sectional descriptive study was conducted at Kamal Al-Samarrai Hospital for Fertility and Infertility in Baghdad from November 2023 to November 2024 to investigate infertility-related stress among 385 women diagnosed with infertility. Data were collected through interviews using the modified infertility-related stress questionnaire, and validity and reliability were established through expert ratings and a pilot study. Statistical analysis was performed using IBM SPSS 20.0, employing techniques such as Pearson correlation, Regression, and Kruskal-Wallis assessments. The results indicate that the majority (97.1%) reported moderate infertility-related stress, with an average stress rating of 92.96. An inverse relationship was observed between age and infertility-related stress, indicating that stress tends to decrease with age (r= -0.151, P=0.003). Additionally, a statistical analysis showed that infertility-related stress levels differed significantly based on education level (P=0.010) and monthly income (P=0.016). The study found mild stress among women with infertility, especially younger, less educated, and lower-income women. The study recommends less expensive counseling, advanced fertility resources, and public awareness to reduce stigma and help affected women improve their health. https://acta.tums.ac.ir/index.php/acta/article/view/11374 https://acta.tums.ac.ir/index.php/acta/article/download/11374/5963