Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 24 3-4 1982 12 15 115 129 SHARIAT F. SHAMIMI K. 2015 09 28 The peutz-Jeghers syndrome is characterized by an association of gastrointestinal polyposis with rnelain spots on oral mucosa, lips, and skin. This symdrorne is inherited as a simple mendelian autosomal dominant trait. Intussusception is by far the most common complication. Although these polyps are widely regarded as hamartomas and rarely undergo malignant change, they have been reported to be associated with carcinoma of gastrointestin and ovary. In the case reported here, the cancer developed from hamartomatous polyps. https://acta.tums.ac.ir/index.php/acta/article/view/167 https://acta.tums.ac.ir/index.php/acta/article/download/167/163