Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 36 2 1998 12 15 102 105 D. Qujeq 2015 09 28 Gamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. Measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value. The liquid chromatography (LC) system consisted of a delivery pump. Male rats (150-250g) were used in this study. The brain was rapidly removed from decapitated animals. Trie chromatograms showed satisfactory resolution and symmetrical peak shapes, both with the standard and tissue extracts. the retention lime was 4.60 min. it was constant in repeated analyses and exactly the same for the standard and tissue samples. https://acta.tums.ac.ir/index.php/acta/article/view/1751 https://acta.tums.ac.ir/index.php/acta/article/download/1751/1744