Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 38 2 2000 06 15 87 88 Ghazizadeh S Behtash N Ghaem Maghami F Modares M Moosavi A 2015 09 28 Gestational Trophoblastic Neoplasia ( GTN) is one of the most common gynecologic tumors in our country. Despite development of effective chemotherapy: some cases remain resistant and if there is only focus of tumor, resection would be indicated.We present a young woman with stage 1 persistant GTN showing no response to chemotherapy. Transvaginal sonograpy revealed trophoblastic tissue in the uterus. Metastatic work up was negative. Tumor was resected by hyteroresectoscopy, and there was no need for subsequent chemotherapy, BHCG remained negative after 26 months of follow up. https://acta.tums.ac.ir/index.php/acta/article/view/2290 https://acta.tums.ac.ir/index.php/acta/article/download/2290/2280