Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 40 2 2002 06 15 132 135 Motesaddi Zaranadi M Givehchi G 2015 09 28 Lip pits are among the rarest congenital deformities recorded. Initially reported in 1845, it’s familial occurrence has been reported just once. These developmental anomalies occur either as an isolated defect or in association with other developmental deformities including cleft lip, cleft palate or both. It may be located at the commisures of the lips or in the midline of the lower lip. It is often inherited as an autosomal dominant trait with variable penetrance.Our report of a family in which all of the three children (two girls and a boy) and their father wre involved in concert with the latter statement. https://acta.tums.ac.ir/index.php/acta/article/view/2596 https://acta.tums.ac.ir/index.php/acta/article/download/2596/2578