Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 42 5 2004 10 15 379 382 T. Mashhoodi S. Zahedi-Asl AR. Sarkaki 2015 09 28 It has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. The exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and cardiovascular disorders. To determine the probable effect of aluminium on vasculature function, in vitro effects of aluminium ion on vasoconstriction induced by KCl (30 mM) or phenylephrine (10 µM) were investigated using isolated rat aorta. AlCl3 (1-4 mM) decreased both KCl and phenylephrine induced contractions in a dose dependent manner (P https://acta.tums.ac.ir/index.php/acta/article/view/2756 https://acta.tums.ac.ir/index.php/acta/article/download/2756/2738