Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 44 1 2006 02 15 59 62 F. Asgarani M. Keyhani R. A. Sharifian G. R. Toogeh R. Aghanouri H. Jalaeekhoo 2015 09 28 Castleman’s disease (angiofollicular lymphoid hyperplasia) includes a heterogeneous group of lymphoproliferative disorders. The cause of this disease remains uncertain. There are two types of localized Castleman’s disease: the more common hyaline vascular and the plasma cell types. Mixed variant is an uncommon localized lesion in general population. The lesions can occur in any part of the body that contains lymphoid tissue, although seventy percent are found in the anterior mediastinum. We report a thirty years old boy with Castleman’s disease who presented with fever, anorexia, weight loss,sweating, anemia and abdominal mass. The histologic examination of the biopsy specimens revealed a mixed hyaline vascular and plasma cell type of Castleman’s disease. https://acta.tums.ac.ir/index.php/acta/article/view/3142 https://acta.tums.ac.ir/index.php/acta/article/download/3142/3122