Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 45 6 2007 12 15 437 442 M. Sadeghi A. Mehr-Aein 2015 09 28 Extensive blood loss in total hip surgery is well known and is associated with a high transfusion rate of allogeneic blood. The aim of this study is to assess the effects of intraoperative tranexamic acid on post-operative bleeding and need for allogeneic transfusion during hip fracture surgery. We investigated 67 patients undergoing hip fracture surgery in a prospective, randomized, double-blinded study. 32 patients received tranexamic acid (TA) given in a bolus dose of 15 mg/kg before surgical incision. The remaining, 35 patients were allocated as control group. Postoperative bleeding, transfusions, complications, and hospital stay were recorded. The intraoperative bleeding was significantly lower in the TA group (652 ± 228 ml vs. 1108 ± 372 ml, p https://acta.tums.ac.ir/index.php/acta/article/view/3313 https://acta.tums.ac.ir/index.php/acta/article/download/3313/3291