Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 6 2008 12 15 501 506 R Yegane Department of Surgery, Loghman Hakim Hospital, School of Medicine, Shaheed Beheshti University of Me H Peyvandi Department of General Surgery, Loghman Hakim Hospital, School of Medicine, Shaheed Beheshti Universi E Hajinasrollah Department of Surgery, Loghman Hakim Hospital, School of Medicine, Shaheed Beheshti University of Me N Salehei Department of General Surgery, Loghman Hakim Hospital, School of Medicine, Shaheed Beheshti Universi M Ahmadei Department of Social Medicine, School of Medicine, Shaheed Beheshti University of Medical sciences, 2015 09 28 Various scoring systems have been devised to aid diagnosis of acute appendicitis. The main objective of this study was finding the accuracy of modified Alvarado score in prediction of acute appendicitis. The registries of cases with appendectomy, who had been admitted to a referral medical center in the capital of Iran from February 2000 to March 2004, were studied. Sensitivity and specificity of modified Alvarado scoring and clinical diagnostic system used in our center were calculated. ROC curve analysis demonstrated increasing chance of acute appendicitis by increasing of the modified Alvarado score (P = 0.001), but it was neither sensitive nor specific (sensitivity, 55%; specificity, 59%). Diagnosis based on surgeons' decision was more sensitive than Alvarado scoring (sensitivity 93-95% in different age groups). Diagnosis of acute appendicitis based on surgeons' decision is more helpful than modified Alvarado score.   https://acta.tums.ac.ir/index.php/acta/article/view/3528 https://acta.tums.ac.ir/index.php/acta/article/download/3528/3504