Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 47 5 2009 10 15 431 433 EN Niromanesh Shirin Departements of Obstetrics and Gynecology, Mirza Koochak khan Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Mirzaie Fatemah Departements of Obstetrics and Gynecology, School of Medicine, Kerman University of Medical sciences, Kerman, Iran. Bateni Alireza Departments of Pathology, Erfan Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Liposarcoma is a mesenchymal malignant tumor and is the second-most common soft tissue sarcoma in adults. Primary peritoneal liposarcoma is very rare. We report a case of abdominal liposarcoma originating from peritoneum in 57-year old woman, presenting with hugeness of abdomen.  The symptoms had been begun from one month ago without any pain, discomfort or gastrointestinal symptoms. In physical examination a large mass with approximate size of 30×35 cm and firm density was found in left lower part of abdomen. The patient underwent laparotomy. The pathologic diagnosis was well differentiated liposarcoma. After 5 months of treatment the patient is well and no problem, complication or recurrence has been reported. https://acta.tums.ac.ir/index.php/acta/article/view/3622 https://acta.tums.ac.ir/index.php/acta/article/download/3622/3598