Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 47 6 2009 12 15 479 483 EN Houshang Gerami Department of Otolaryngology, Head and Neck Surgery, Guilan University of Medical Sciences, Guilan, Iran. Nasim Kousha Department of Otolaryngology, Head and Neck Surgery, Guilan University of Medical Sciences, Guilan, Iran. 2015 09 28 Leprosy is an infectious and non-fatal disease that mainly involved skin and peripheral nervous system and caused by Mycobacterium Lepra. This case is a 41-year-old woman with intermittent nasal bleeding and a mass (1.5×2.5 cm) in the right side of lateral nasal wall and a (1×1 cm) mass on septum in the left side of the nose. Considering the probability of intranasal tumor, endoscopic biopsy for histopathologic examination had been done and the result confirmed the diagnosis of leprosy. After unexpected proving of pathologic leprelepromatose, the patient put under 3-drug- treatment. https://acta.tums.ac.ir/index.php/acta/article/view/3633 https://acta.tums.ac.ir/index.php/acta/article/download/3633/3609