Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 48 1 2010 02 15 High Prevalence of Chronic Hepatitis B Infection among Injection Drug Users in Iran: The Need to Increase Vaccination of Adults at Risk 58 60 EN Seyed Ahmad SeyedAlinaghi Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. Parastoo Kheirandish Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. Nazli Karami Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. Sepehr Salem Urology Research Center, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Hadi Shirzad Research Center-Head Quarter of Police Force Medicine, Tehran, Iran. Mohammad Reza Jahani Department of Medicine, Baghiyat-Allah University of Medical Sciences, Tehran, Iran. Mohammad Reza SeyedAhmadian Research Center-Head Quarter of Police Force Medicine, Tehran, Iran. Pegah Valiollahi Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. Mostafa Hosseini Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Minoo Mohraz Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. Willi McFarland Department of Epidemiology and Biostatistics, University of California, San Francisco, USA. 2015 09 28 We measured the prevalence of HBV surface antigen (HBsAg) among male injection drug users (IDUs) in Detention, Tehran, Iran. A cross-sectional survey included 499 male IDUs arrested by police during a predetermined police sweep in Tehran (February, 2006). A questionnaire was filled out for each individual. Blood specimens were collected for HBsAg testing. Prevalence of HBsAg was 5.8% (95% CI 3.6-7.9). The majority of chronic HBV infections, 69.2%, were among adults age 25 to 34 years. The high prevalence of HBsAg highlights the need for special efforts to increase vaccination among adult populations at risk for HBV infection in order to reducing continuing transmission and stave off future high burden of disease. https://acta.tums.ac.ir/index.php/acta/article/view/3648 https://acta.tums.ac.ir/index.php/acta/article/download/3648/3623