Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 48 2 2010 04 15 111 116 EN Ali Arab Kheradmand Department of Surgical Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran. Neda Ranjbar Novin Research Development Center, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran. Ramesh Omranipour Department of Surgical Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran. 2015 09 28 Closure of fascia after transverse rectus abdominis musculocutaneous (TRAM) flap has usually been performed with direct closure or synthetic material. The dermal autograft was removed from zone IV of flap was an alternative to reinforce fascial closure. The dermal autograft was used in 34 patients after TRAM harvest for breast, head and neck reconstruction and Prolene mesh was used in 42 other patients for closure of fascial defect. All patients were followed by physical examinations. Average follow-up in the dermal autograft group was 27.3 versus 20.7 months in the second group. In the dermal autograft group, one patient complained of bulging of the anterior abdominal wall; one developed a wound infection. In the second group, one patients experienced true hernia. Dermal autografts are a useful alternative to mesh repair of fascial defects after TRAM flap harvest. https://acta.tums.ac.ir/index.php/acta/article/view/3660 https://acta.tums.ac.ir/index.php/acta/article/download/3660/3635