Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 48 2 2010 04 15 117 122 EN Khosrow Hashemzadeh Department of Cardiovascular Surgery, Cardiovascular Research Center, Shahid Madani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. Shahryar Hashemzadeh Department of General and Thoracic Surgery, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. 2015 09 28 The purpose of this study was to evaluate the early and late outcome after total correction of tetralogy of fallot (TOF) in 101 consecutive patients with a mean age of 8.23 ± 4.90 years underwent repair of surgery at one institution between 1995 and 2006. Forty two patients had initial palliative operations. A transannular patch was inserted in 60 (58.5%) patients. Risk factors for operative mortality were analyzed. Followup was obtained from clinical appointments and telephone questionnaires. The operative mortality was 6.9%. Aortic cross-clamp time more than 90 minutes (P<0.01) and cardiopulmonary bypass time more than 120 minute (P<0.01), affected operative mortality, whereas previous palliative procedure, hematocrit level, and use of transannular patch did not. Mean follow-up is 34.08 ± 31.09 months (range, 1 month to 120 months). Actuarial survival is 91% alive 10 years after total correction. On Postoperative echocardiography, 22 patients had mild pulmonary regurgitation, 19 had a right ventricular outflow tract gradient more than 50 mmHg, and 10 had a small residual ventricular septal defect. There were two late deaths. Late sudden death from cardiac causes occurred in one patients. Total correction of TOF can have low operative mortality and provide excellent long-term survival. This experience suggests that the key factor in the total correction of TOF is to correct the pathology completely, to protect the myocardium, and to manage the complication properly. https://acta.tums.ac.ir/index.php/acta/article/view/3661 https://acta.tums.ac.ir/index.php/acta/article/download/3661/3636