Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 48 3 2010 06 15 196 197 EN Hamdollah Karamifar Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran. Satila Dalili Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran. Zohreh Karamizadeh Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran. Gholamhosein Amirhakimi Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran. Hosein Dalili Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran. 2015 09 28 Autoimmune polyglandular syndrome (APS) type 2 is characterized by the presence of Addison's disease, in association with autoimmune thyroid disease and/or type 1 diabetes mellitus. APS type 2 occurs most often in middle aged females and is rare in children. Here an 11 year old boy is reported with Addison's disease who developed symptom's of diabetes mellitus, goiter, malabsorption, macrocytic anemia and keratitis. APS type 2 occurs most often in middle aged females and is quite rare in children but one should think to autoimmune poly glandular syndrome type II in patient at any age especially in patients with Addison's disease. https://acta.tums.ac.ir/index.php/acta/article/view/3677 https://acta.tums.ac.ir/index.php/acta/article/download/3677/3652