Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 1 2011 01 15 21 24 EN Leila Sekhavat Department of Obstetrics & Gynecology, Shaheed Sadoughi Hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran. Motaharah Golestan Department of Pediateric, Shaheed Sadoughi Hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran. Razieh Fallah Department of Pediateric, Shaheed Sadoughi Hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran. 2015 09 28 The objective of this study was evaluation of excessive pregnancy weight gain effect in non-diabetic women with normal pre-pregnancy BMI on macrosomia of neonate. In a descriptive cross-sectional study, neonate weighs of all term pregnancy in non-diabetic women with normal pre-pregnancy BMI delivered from 2002 to 2004 in Shaheed Sadoughi Hospital in Yazd, were evaluated. Compared with mothers with normal pregnancy weight gain, the risk of macrosomia in offsprings was significantly elevated in women who had excess weight gain. The odds ratio (OR) was 3.3 (95% confidence interval [CI] = 2.2 - 5.1, P = 0.0001). Given the complications associated with delivering large babies, women may benefit from not gaining excess weight in pregnancy. https://acta.tums.ac.ir/index.php/acta/article/view/3685 https://acta.tums.ac.ir/index.php/acta/article/download/3685/3660