Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 4 2011 04 15 252 257 EN SeyedAhmad SeyedAlinaghi Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Sara Jam Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Farhad Mehrkhani Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Fatemeh Fattahi Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. AND Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Duman Sabzvari Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Zahra Kourorian Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. AND Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Hossain Jabbari Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Minoo Mohraz Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 We carried out a study to determine the seroprevalence of HBV and HCV infections in HIV positive patients at a main referral center for HIV/AIDS in Iran. Serum samples from 201 HIV positive patients referring to a referral center for HIV/AIDS were analyzed for the presence of some hepatitis B (HBsAg, anti-HBc, anti-HBs) and Hepatitis C (anti-HCV) markers, during 2004- 2005. HBsAg was positive in 27 patients (13.4%), anti-HBc was positive in 60 patients (29.8%) and anti-HBs in 23 patients (11.4%). Anti-HCV Ab was positive in 135 of 201 (67.2%). HBV and HCV coinfection was observed in 73 of 201 (36.3%). The maximum prevalence of HBV-HIV and HCV-HIV coinfections were seen in intravenous drug users; 61.2% and 85.1%, respectively (P<0.0001). The minimum prevalence of HBV-HIV and HCV-HIV were seen in HIV patients´wife (HIV+ patients who were infected by monogamous sexual contact with their HIV positive husband) both of them were 8% (P<0.0001). This study showed that HBV-HIV and HCV-HIV coinfections are significant in patients with HIV/AIDS in Iran. A greater relevance was observed in the association between HCV and HIV. This study suggests that it is necessary to investigate risk factors and risk groups for these infections in Iran. https://acta.tums.ac.ir/index.php/acta/article/view/3733 https://acta.tums.ac.ir/index.php/acta/article/download/3733/3708