Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 6 2011 06 15 396 398 EN Fariba Yarandi Department of Gynecological Oncology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Zahra Eftekhar Department of Gynecological Oncology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Hadi Shojaei Department of Gynecological Oncology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Fatemeh Rahimi-Sharbaf Department of Obstetrics and Gynecologist, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Fatemeh Baradaran Department of Radiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Placenta increta, a rare complication of pregnancy, is associated with significant postpartum hemorrhage often requiring emergency hysterectomy. We report a case of conservative management, with a combination of parenteral methotrexate, serial ultrasound and β-hCG assessment. Serum β-hCG levels were undetectable after 8 weeks of therapy. A scan at 6 months showed complete involution of the uterus. Review of the literature discussing the diagnostic tools, clinical features, management and outcome of pregnancies with placenta increta. https://acta.tums.ac.ir/index.php/acta/article/view/3763 https://acta.tums.ac.ir/index.php/acta/article/download/3763/3738