Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 438 441 EN Mohammad Reza Hadji Abadi Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Ghodsi Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Masoud Merazin Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Hadi Roozbeh Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007. Pituitary hormones were assessed 3 and 6 months after injury. In 3rd month post-injury, 39 cases had not any pituitary dysfunction; however, deficiencies in one, two and three of the pituitary hormones were found in 26, 8 and 2 patients, respectively. Twenty one patients showed a deficiency in one of the pituitary hormones and only one case with deficiency of two after 6 months. The most prevalent changes occur in IGF-1 and LH/FSH after moderate TBI. However, the whole deficiencies decrease over the time. https://acta.tums.ac.ir/index.php/acta/article/view/3771 https://acta.tums.ac.ir/index.php/acta/article/download/3771/3746