Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 8 2011 08 15 560 564 EN Siamak Afshinmajd Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. Alireza Khalaj Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. Younes Roohani Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. Mohammadebrahim Yarmohammadi Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. Shadi Salehpour Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. Alireza Saeedi Department of Physiotherapy, Mostafa Khomeini Hospital, Shahed University, Tehran, Iran. Gholam Hossein Ghaedi Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. Mehran Heydari Seradj Mostafa Khomeini Hospital, School of Medicine, Shahed University, Tehran, Iran. 2015 09 28 Acute paraplegia is a rare but catastrophic complication of surgeries performed on aorta and corrective operations of vertebral column. Trauma to spinal cord after spinal anesthesia and ischemia of spinal cord also may lead to acute paraplegia. Acute paraplegia as a complication of general anesthesia in surgeries performed on sites other than aorta and vertebral column is very rare. Here we present a 56 year old woman with acute paraplegia due to spinal cord infarction after laparoscopic cholecystectomy under general anesthesia probably caused by atherosclerosis of feeding spinal arteries and ischemia of spinal cord after reduction of blood flow possibly due to hypotension during general anesthesia. https://acta.tums.ac.ir/index.php/acta/article/view/3796 https://acta.tums.ac.ir/index.php/acta/article/download/3796/3771