Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 50 1 2012 01 15 26 30 EN Younes Nozari Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Nader Jangi Oskouei Department of Cardiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Zahra Khazaeipour Research Deputy of Imam Khomeini Hospital Complex, Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Coronary artery disease is one of the most common causes of mortality and morbidity across the world. Its treatment includes medical treatment, coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI). The purpose of this study was to investigate the effect of PCI on echocardiographic findings of left ventricular (LV) systolic and diastolic function. 115 patients with coronary artery disease candidate for PCI were enrolled to our study. Echocardiography was done before PCI, the day after and 3-6 months later. LV systolic and diastolic function were measured and recorded. Echocardiographic finding compared with repeated measurement analysis. Mean age of the patients was 57.8±8.38 years. The mean Ejection Fraction (EF) was (%40.52±6.36) before, (%41.83±7.14) the day after, and (%44.0±7.89) 3-6 months after PCI. Diastolic dysfunction were mild to moderate before PCI, which in %74 (86 patients) were improved to mild dysfunction the day after PCI but not changed 3-6 months later (P<0.0001). PCI improved LV ejection fraction, and LV diastolic function in our patient’s population. https://acta.tums.ac.ir/index.php/acta/article/view/3854 https://acta.tums.ac.ir/index.php/acta/article/download/3854/3829