Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 50 3 2012 03 15 213 215 EN Zakaria Zakariaei Department of Medical Sciences and Toxicology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Shervin Taslimi Department of Psychiatry, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Amin Tabatabaiefar Department of Medical Genetics, School of Medicine, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran. Mosa Arghand Dargahi Department of Medical Sciences and Toxicology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Drug induced dystonic reactions are among common presentations of patients in emergency departments, and typically occur with antidopaminergic agents as their extra-pyramidal side effects. Dystonic reactions usually occur within the first few hours or days after commencing a drug or dose increase. Unlike other extra-pyramidal side effects, a patient may experience acute dystonic reactions (ADRs) with the administration of just a single dose. Oromandibular dystonia is a subtype of dystonia which can present with perioral manifestations. In extreme cases, it can lead to temporomandibular dislocation. Haloperidol, as a high potent typical antipsychotic drug, can induce dystonia with blocking D2 dopamine receptors. The present paper reports a case of bilateral dislocation of temporomandibular joint following ingestion of haloperidol in a suicidal attempt in a 17 years old girl. https://acta.tums.ac.ir/index.php/acta/article/view/3885 https://acta.tums.ac.ir/index.php/acta/article/download/3885/3860