Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 48 6 2010 12 15 403 406 EN Nasser Safaie Cardiovascular Research Center, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Reza Ghotaslou Department of Microbiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Hosain Montazer Ghaem Department of Cardiovascular Surgery, School of Medicine, Bandarabass University of Medical Sciences, Bandarabass, Iran. 2015 09 28 Inflammation plays a major role in coronary artery disease (CAD). Currently, it is unclear, whether Cytomegalovirus (CMV) infection is associated with the risk of the atherosclerosis. The aim of this study was to determine the prevalence of anti- CMV antibodies in CAD and non CAD patients undergoing artery bypass surgery. Sera from 157 patients who underwent coronary angiography were tested for CMV by enzyme linked immunosorbent assay (ELISA) at Madani Heart Hospital, Tabriz University of Medical Sciences, Iran. Our study population was 58.6% male and 41.4% female, with an age range of 38 to 86 years. The prevalence of CMV positivity tended to be higher in coronary artery diseases patients than in those without non coronary artery diseases (83.2% versus 63.6%) (P= 0.01). This analysis demonstrated that CMV seropositivity may be a risk factor for CAD in the present study population. https://acta.tums.ac.ir/index.php/acta/article/view/4073 https://acta.tums.ac.ir/index.php/acta/article/download/4073/4048