Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 0 0 1973 12 15 21 28 K. Amoli Vahideh Tabibi 2015 09 28 A case of massive actinomyco tic empyema, the fi rst report in Iran, in a girl of 20 yea rs o ld is presented with complete cu re after treatment by d rainage, penici llin and te tra cycl ine. The pathogenesis of actinornycetes and of o ther saprophytes is d iscu ssed. Altho ugh the incidence of actinomycosis has decreased in the a ntibiotic era, the possib ility of the infection should be kept in mind especia lly in rural a reas for a serio us infection that is easily treatable. https://acta.tums.ac.ir/index.php/acta/article/view/4165 https://acta.tums.ac.ir/index.php/acta/article/download/4165/4140