Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 51 10 2013 10 15 730 732 EN Zahra Ahmadinejad Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Zahra Ghetmiri Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mehrnaz Rasoolinejad Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. AND Iranian Research Centre for HIV/AIDS. 2015 10 11 Patients with human immunodeficiency virus (HIV) infection receiving antiretroviral therapy (ART), despite a reduced viral load and improved immune responses, may experience clinical deterioration. This so called "immune reconstitution inflammatory syndrome (IRIS)" is caused by inflammatory response to both intact subclinical pathogens and residual antigens. Cytomegalovirus retinitis is common in HIV-infected patients on ART with a cluster differentiation 4 (CD4+) counts less than 50 cells/mm3. We reported a patient with blurred vision while receiving ART. She had an unmasking classic CMV retinitis after ART. https://acta.tums.ac.ir/index.php/acta/article/view/4372 https://acta.tums.ac.ir/index.php/acta/article/download/4372/4439