Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 52 8 2014 08 15 601 606 EN Akram Beheshti Department of Dermatology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Hodda Ghadami Department of Dermatology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Ameneh Barikani Department of Community Medicine, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Fatemeh Haj Manouchehri Department of Pathology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. 2015 10 11 Vitiligo Vulgaris is a pigment disorder as the lack of skin pigmentation which its most prevalent cause is autoimmune. Vitamin D has various effects on the natural and acquired immune of the body because of its effectiveness on the T cells and B cells, macrophages and dendritic cells.The object of this study was assessment of the Vitamin D in patients with vitiligo vulgaris in dermatologic clinics in Qazvin in 2012. The 100 patients with Vitiligo were studied through a cross-sectional study. The required data were collected by the questionnaire (age, gender, job, family background, consumption of the dairies and vitamin D supplements), examination (type of skin) and para clinical test (measurement of the serum 25-hydroxyvitamin D level). The 42 (42%) and 58 (58%) people of the population under study were respectively male and female. The mean age of the population under study was 28.7±1.17. The mean serum of 25-hydroxyvitamin D level was 42±24.14 which had a significance difference with a normal level (p<0.04). The mean serum 25-hydroxyvitamin D level among patients with Vitiligo had a significance difference with a normal level. https://acta.tums.ac.ir/index.php/acta/article/view/4567 https://acta.tums.ac.ir/index.php/acta/article/download/4567/4284