Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 52 3 2014 03 15 238 239 EN Maryam Sadat Sadati Department of Dermatology, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Iman Ahrari Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. 2015 10 11 There is no recommendation for the treatment of herpes zoster neuralgia in pregnancy, as it even sometimes needs administration of strong opioids.Here, we report a pregnant woman with severe zoster neuralgia who responded favorably to acetaminophen. Due to the drug's safe profile and good efficacy, acetaminophen can be used as an alternative for herpetic neuralgia in pregnant women. However, controlled studies are still needed. https://acta.tums.ac.ir/index.php/acta/article/view/4662 https://acta.tums.ac.ir/index.php/acta/article/download/4662/4341