Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 53 4 2015 04 15 246 249 EN Tugce Ozlem Kalayci Department of Radiology, Malatya Beydagi Government Hospital, Malatya, Turkey. Ayşe Nur Akatlı Department of Pathology, School of Medicine, Malatya, Turkey. Fitnet Sönmezgöz Department of Radiology, Malatya Beydagi Government Hospital, Malatya, Turkey. Emine Türkmen Şamdancı Department of Pathology, School of Medicine, Malatya, Turkey. 2015 10 11 Giant uterine leiomyomas are extremely rare neoplasms and are challenging both diagnostically and therapeutically. A 49-year-old premenopausal female presented at our Department complaining of abdominal pain and distention for several years. Ultrasound (US), color Doppler US, abdominal computed tomography imaging after administration of contrast material, and abdominal magnetic resonance imaging were performed. Histopathologic examination revealed a pedunculated subserosal uterine leiomyoma. In this case report, we present abdominopelvic multimodal radiologic imaging findings of our patient with a giant subserosal uterine leiomyoma, in conjunction with histopathological findings. https://acta.tums.ac.ir/index.php/acta/article/view/4898 https://acta.tums.ac.ir/index.php/acta/article/download/4898/4445