Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 55 8 2017 10 07 533 535 EN Mohammadreza Sobhan Department of Dermatology, Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Pedram Alirezaei Department of Dermatology, Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Mahmood Farshchian Department of Dermatology, Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Gholamreza Eshghi Department of Dermatology, Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Hamid Reza Ghasemi Basir Department of Pathology, Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Leila Khezrian Department of Dermatology, Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. 2015 10 31 2016 10 08 White sponge nevus is a rare benign autosomal dominant disorder with variable penetrance. It is characterized by asymptomatic white plaques affecting mainly the oral mucosa. Careful clinical and histopathological examination is indicated to exclude other more serious conditions presenting as oral white lesions. Herein, we present a new case of oral white sponge nevus in a 17-year-old Iranian male with no familial background. https://acta.tums.ac.ir/index.php/acta/article/view/5100 https://acta.tums.ac.ir/index.php/acta/article/download/5100/4980