Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 55 2 2017 02 21 139 141 EN Farzaneh Najafi Department of Internal Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Parichehr Kafaie Department of Dermatology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Hossein Neamatzadeh Mother and Newborn Health Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. 2015 11 17 2016 02 16 Kaposi᾽s sarcoma (KS) can develop in 0.06% to 4.1% of kidney transplant recipients. Here we describe a case of 50-year-old man who developed KS a few months after kidney transplantation. After transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (ATG) for five days. At the discharge, his immunosuppressive therapy was prednisolone 20 mg/day, tTacrolimus (Pprograf®) 4 mg/day, and mycophenolate mofetil (MMF) 2 gr/day, while he also took Vvalcyte and diltiazem. Once diagnosed with KS, the Prograf® (tacrolimus)  was replaced by prednisolone (5 mg/day) and sirolimus (2 mg/day). Gradually the skin nodule on the patient arm disappeared, and the others nodule on the right his leg was decreased. It seems that the examination of skin should be a part of regular follow-up and dermatologist examination is recommended every 6 months. https://acta.tums.ac.ir/index.php/acta/article/view/5156 https://acta.tums.ac.ir/index.php/acta/article/download/5156/4905