Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 55 9 2017 10 30 591 593 EN Rana Rafiei Department of Dermatology, Skin Research Center, Guilan University of Medical Sciences, Rasht, Iran. Hojat Eftekhari Department of Dermatology, Skin Research Center, Guilan University of Medical Sciences, Rasht, Iran. Siamak Granmayeh Department of Dermatology, Skin Research Center, Guilan University of Medical Sciences, Rasht, Iran. Nahid Nickhah Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran. Behnam Rafiee Department of Pathology, NYU Winthrop Hospital, Mineola, NY, USA. 2015 11 26 2016 03 04 Extramammary Paget’s disease is an uncommon intraepithelial adenocarcinoma in genital and perianal regions. Genital wart is the most common sexually transmitted disease caused by human papilloma viruses and vulval lichen sclerosus is chronic pruritic dermatitis in genital area which could be able to change to invasive squamous cell carcinoma. We report a patient who had simultaneous lichen sclerosus, genital wart and extramammary Paget’s disease of the vulva. We could not find any significant association between them in literature. https://acta.tums.ac.ir/index.php/acta/article/view/5199 https://acta.tums.ac.ir/index.php/acta/article/download/5199/4992