Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 54 4 2016 05 10 283 285 EN Maryam Ameri Department of Forensic Medicine and Toxicology, Iran University of Medical Sciences, Tehran, Iran. Shahrokh Mehrpisheh Department of Neonatology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Azadeh Memarian Department of Forensic Medicine and Toxicology, Iran University of Medical Sciences, Tehran, Iran. Payam Balvayeh Department of Pathology, Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran. 2016 04 19 Fatty liver disease (FLD) is the most prevalent form of liver disease worldwide. Overnutrition can induce nonalcoholic fatty liver disease (NAFLD), a spectrum of conditions ranging from simple steatosis [or nonalcoholic fatty liver (NAFL)] to nonalcoholic steatohepatitis and cirrhosis. Some of the epidemiological and pathological studies have also suggested an association between the presence of fatty liver and sudden death. A 37-year-old man was found dead when he was asleep in the bed at home. According to his family, he was single and a costermonger. He was not an athlete, and there was no history of any physical and mental disorder. He was not addicted and did not use any drugs or alcohol. The positive points, in this case, were: a large heart with mild coronary stenosis and steatohepatitis in autopsy and sudden death. Since steatohepatitis did not have any complication such as fat embolism, it can be concluded that the combination of steatohepatitis and cardiovascular disorder led to sudden unexpected death. Heart more than 450 gr is susceptible to arrhythmia, and fatty liver disease can cause cardiovascular changes. https://acta.tums.ac.ir/index.php/acta/article/view/5586 https://acta.tums.ac.ir/index.php/acta/article/download/5586/4782