Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 56 2 2018 02 17 127 131 EN Gholamreza Sivandzadeh Department of Gastroenterology, Gastroenterology and Hepatology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. Alimohammad Banazadeh Department of Surgery, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. Amir Anushiravani Department of Gastroenterology and Hepatology, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2016 11 24 2017 05 07 Foreign bodies are commonly ingested and usually pass through the gastrointestinal tract, but in less than 1% complications can be seen. We aimed to report a very rare case of multiple hepatic abscesses caused by perforation of the sigmoid colon due to a chicken bone. An 82-year-old man presented with a 5-day history of abdominal pain, fever, and coffee ground vomiting. He was febrile and tachycardic and had a mild localized abdominal tenderness in the left lower quadrant. Laboratory findings revealed a lymphocyte dominant leukocytosis with an elevated erythrocyte sedimentation rate. Multiple abscesses were shown in the right lobe of the liver in abdominal computed tomography. Colonoscopy showed a chicken bone perforating both walls of the sigmoid colon. He received broad-spectrum antibiotics and underwent surgery for a complete recovery. Chronic lymphocytic leukemia was diagnosed by flow cytometry phenotyping. Mortality and morbidity of hepatic sepsis caused by foreign body-induced colon perforation depend on a rapid diagnosis.  We presented a very rare condition that should always be kept in mind when dealing with a case of liver abscess and even while confronting septic shock with an unknown origin. https://acta.tums.ac.ir/index.php/acta/article/view/6031 https://acta.tums.ac.ir/index.php/acta/article/download/6031/5057