Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 56 8 2018 11 26 544 546 EN Ahmad Bahrami Department of Allergy, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran. Mahnaz Sadeghian Department of Pediatrics, Ali-Asghar Hospital, Iran University of Medical Sciences, Tehran, Iran. Mehrdad Sheikhvatan Research and Development, Iran University of Medical Sciences, Tehran, Iran. Arash Foroudi Department of Allergy, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran. Sara Harsini Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. Nima Rezaei Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. AND Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. 2017 05 28 2017 07 29 Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence. https://acta.tums.ac.ir/index.php/acta/article/view/6487 https://acta.tums.ac.ir/index.php/acta/article/download/6487/5143