Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 56 11 2019 01 16 732 735 EN Vikram Rajput Department of Surgery, MIMSR Medical College, Latur, India. Basavraj Warad Department of Surgery, MIMSR Medical College, Latur, India Vijay Chincholkar Department of Microbiology, Govt. Medical College, Latur, India. Milind Davane Department of Microbiology, MIMSR Medical College, Latur, India. Basavraj Nagoba Department of Microbiology, MIMSR Medical College, Latur, India. 2017 08 03 2017 12 19 Actinomycosis is a chronic granulomatous bacterial disease. It has a tendency to spread contagiously and suppurate forming granulation tissue, and multiple abscesses, which drain through skin forming sinus tracts. Sulphur granules discharging through sinus tracts are the characteristic features. Its varied presentation is always confused with malignancy rather than an infective process. We report an extraordinary case of recurrent abdominal wall actinomycosis spreading to the liver, right kidney, intestine,and pelvic organs because of discontinued treatment with penicillin. We emphasize the importance of long-term antibiotic treatment, which if deferred can lead to recurrence of the disease which could be life threatening at times. https://acta.tums.ac.ir/index.php/acta/article/view/6626