Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 3 4 1960 12 15 19 25 F. Shafa 2015 09 28 1) Fifty coagulase posittve strains of staphylococc~~ ~folated fr.o~ .the nose and wrist of Hospital nurses have been examined for sensltfvlty to pemcilhn, tetracyclines, chloramphenicol, dihydrostreptomycin, erythrorriycm, neomycin, kana.n:ycin, bacitracin, polymyxin-B and the triple sulfa. The percentages of fully sensittve strains at the present are as followe:                                       Erythromycin                                       100% Neomycin                                             78% Kanamycin                                            78% Chloramphenicol                                     68% Dihydrostreptomycin                               52% Penicillin                                                18% Tetracyclines                                         16% Polymyxin-B                                            1% Triple sulfa                                              0% 2) The following topics have been discussed: a) The origin anr" mechanism of drug resistance b) Cross-resistr.nee c) The hospital epidemiology of Staphylococcus d) The clinical implications of Staphylococcus drug-resistance https://acta.tums.ac.ir/index.php/acta/article/view/70 https://acta.tums.ac.ir/index.php/acta/article/download/70/66