Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 56 10 2019 01 13 660 664 EN Mehrdad Goodarzi Department of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Hossein Ali Khazaei Department of Clinical Immunology, Clinical Immunology Research Center (CIRC), Zahedan University of Medical Sciences, Zahedan, Iran. Bahar Ashjaei Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran . Maryam Ghavami Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran . Mansour Mollaeian Department of Surgery, School of Medicine, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Nora Bigdeli Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran . Ali Talebi Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Azita Parvizizadeh Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Gholamreza Badfar Department of Pediatric, School of Medicine, Ahvaz University of Medical Sciences, Ahvaz, Iran. Alireza Ebrahim Soltani Department of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Alireza Nahvi Department of Biomedical Engineering, School of Engineering, Shahed University, Tehran, Iran. Valiullah Mehrabi Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Hedayatollah Nahvi Department of Surgery, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran . 2018 03 17 2018 08 10 Esophageal atresia (EA) is a rare congenital anomaly that may be isolated or associated with other anomalies requiring prompt medical and surgical planning for optimal result. This study was conducted to show our recent experience on the outcome of treated patients in two hospitals affiliated to Tehran University of Medical Sciences (TUMS). From January 2008 to May 2013 records of 43 neonates patients (23 male) with EA admitted in 2 children centers and all related data including demographic, diagnostic associated anomalies, surgical approaches, birth weight, mortality, and complications were collected. Inability of feeding and swallowing was the most common symptoms (in 90,6%), associated CHD (44%), and Type C (EA) was the most common type of EA observed in 86% patients, The mortality rate was 4.7% and most common complication was anastomotic stricture (AS) in 60% of patients. Our study showed that despite improvements in management and survival of an infant with (EA), still sepsis, aspiration pneumonia, prematurity, and low birth weight and severe Congenital Heart Disease (CHD) were independent etiology of death and birth weight < 2.500 gr  has a significant  effect on the occurrence of postoperative complications. https://acta.tums.ac.ir/index.php/acta/article/view/7127 https://acta.tums.ac.ir/index.php/acta/article/download/7127/5171