Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 57 9 2020 04 20 572 574 Parvaneh Dehghan Department of Nursing, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. AND Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. Samaneh Kakhki Department of Nursing, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. AND Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. Maliheh Eshaghzadeh Department of Nursing, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. AND Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. Mohammad Amin Khezri Student Research Committee, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. 2019 07 24 2019 12 24 Although the most common site in Non-Hodgkin's Lymphoma (NHL) is the Waldeyer’s ring, the involvement of the tongue is extremely rare. The present study revealed a 70-year-old female with primary non‑Hodgkin’s lymphoma (NHL) of the base of the tongue with the chief complaint of sore throat and dysphasia as a rare case report. The patient was expired 3 months after diagnosis because of the advanced stage of the disease and poor physical statue. The diagnosis was confirmed as primary NHL diffuse large B cell type by histopathological and immunohistochemistry results. https://acta.tums.ac.ir/index.php/acta/article/view/8010