Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 58 4 2020 07 28 188 191 Maryam Lale Ataei Department of Anatomical Sciences, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Raziyeh Kheirjou Department of Anatomical Sciences, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Susan Mohammadi Department of Radiology, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran. Nastaran Hesam Shariati School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia. Fardin Fathi Cellular and Molecular Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran. Mohammad Bakhtiar Hesam Shariati Department of Anatomical Sciences, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran. 2019 12 11 2020 04 27 Numerous variations of vessels arising from the aortic arch have been reported. One of the common anatomical variations in the right subclavian artery originating as the last branch of the aortic arch. This report demonstrates two cases of the retroesophageal right subclavian artery in an adult male and female. To highlight the significance of a retro esophageal right subclavian artery, especially its clinical and surgical implications. Multi-slice computed tomography (CT) of a case of an anomalous vessel. This report shows a retro esophageal subclavian artery originating as the last branch from the postero-lateral aspect of the thoracic aorta at the vertebral level T4. No abnormality was seen neither in the heart nor in no other vascular system in this region. Radiologists mainly encounter a retroesophageal right subclavian artery incidentally and are usually described as asymptomatic, but several clinical conditions have been associated with this kind of occurrence.     https://acta.tums.ac.ir/index.php/acta/article/view/8216 https://acta.tums.ac.ir/index.php/acta/article/download/8216/5395