Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 58 12 2021 01 04 616 620 Omid Shadkam Department of Gastroenterology and Hepatology, Razavi Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Ali Bahari Department of Internal Medicine, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Mohammadreza Farzanehfar Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Ali Beheshti Namdar Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Mitra Ahadi Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Azita Ganji Department of Internal Medicine, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Ladan Goshayeshi Department of Internal Medicine, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Kambiz Akhavan Rezayat Department of Internal Medicine, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. 2020 03 23 2020 05 05 There are disagreements about the diagnostic value of the current risk stratification systems in patients with acute upper gastrointestinal bleeding (UGIB). The present study aimed to determine the diagnostic value of the Glasgow-Blatchford score in UGIB patients. This study was conducted on 182 patients with UGIB who underwent endoscopy in the Emergency Department of Imam Reza Hospital, Mashhad, Iran. Glasgow-Blatchford Score (GBS) of each patient was estimated by using the clinical and laboratory parameters. The relationship between Blatchford score and endoscopic findings was assessed. Additionally, the sensitivity and specificity of GBS were measured based on high- and low-risk patients. According to the results, GBS had a high sensitivity (90.9%), specificity (79%), as well as positive (76%), and negative predictive values (92.2%). However, no significant relationship was observed between the Glasgow-Blatchford score and re-bleeding. As the findings of the present study indicated, Glasgow-Blatchford was a good predictive method for the determination of the high-risk and low-risk patients with UGIB. Nevertheless, this method showed poor performance in the prediction of re-bleeding. https://acta.tums.ac.ir/index.php/acta/article/view/8371