Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 59 2 2021 02 28 91 96 GholamAbbas Roustaei Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Fatemeh Shomali Department of Medicine, School of Medicine, Babol University of Medical Sciences, Babol, Iran Hemmat Gholinia Department of Biostatistics, School of Medicine, Babol University of Medical Sciences, Babol, Iran. Maral Farzin Department of Medicine, School of Medicine, Babol University of Medical Sciences, Babol, Iran. Seyed Ahmad Rasoulinejad Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. 2020 07 08 2020 10 23 Cataract is a multifactorial ocular disease, resulting in turbidity or opacity of the lens of the eyes, which leads to blindness or reduction of visuality. The different environmental, socio-economical, and lifestyle factors indicate as risk factors of age-related cataracts. The aim of this study was the evaluation of daily activity, dietary regimen, residence location and etc., as risk factors of age-related cataracts. In this census, a cross-sectional study was performed on 353 patients with age-related cataract underwent surgery, who referred to Rouhani Hospital in Babol, Iran from 2018 to 2019, and 343 healthy individuals. The lifestyle-related information was collected from all individuals via the designed questionnaire. Our results showed that there were significant correlations between the birth/residence in the village (comparing to city, P<0.001), abnormal sleeping time (P<0.001), daily activity (and being outdoor, P<0.001), and use of solid oil (P<0.001) with increasing in age-related cataracts. Furthermore, the use of antioxidant-containing fruits significantly reduces the risk of age-related cataracts. Our results established that lifestyle clearly has a golden impact on age-related cataracts. The reduction in daily activity, normal sleeping time, and more use of antioxidant-containing dietary regimen play a preventive role in age-related cataracts. https://acta.tums.ac.ir/index.php/acta/article/view/8614