Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 60 9 2022 11 08 571 574 Amin Dalili Surgical Oncology Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Nasrin Kamali Department of Operating Room, Faculty of Nursing, North Khorasan University of Medical Sciences, Bojnurd, Iran Ali Jangjo Surgical Oncology Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Mostafa Sadeghi Montaseriyeh Dialysis and Transplant Center, Mashhad University of Medical Sciences, Mashhad, Iran Fatemeh Kiyani Far Faculty of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran Sara Mohammadi Department of Operating Room, Faculty of Paramedical, Ilam University of Medical Sciences, Ilam, Iran Masoud Mahdavi Zafarghandi Department of Urology and Renal Transplantation, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran 2020 09 02 2021 12 08 Obesity/bariatric surgery is rising as the most effective treatment for obesity. In previous studies, the history of Helicobacter pylori as the main cause of chronic abdominal pain in patients undergoing bariatric surgery has not been discussed. In this study, we determine in a set of patients how much of the number of people with positive H. pylori before the operation in one year later suffered from chronic abdominal pain. A retrospective study was conducted on 320 patients undergoing bariatric surgery. Data were collected by interviewing and referring to the medical records of patients. Of 320 patients, 125 were H. pylori-positive, and from these numbers, 43 had chronic abdominal pain (34.4%). Although in previous studies of bariatric surgery, the history of H. pylori has not been identified as the main cause of chronic abdominal pain after surgery. However, according to the available evidence in this study, with a prevalence of more than one-third of chronic abdominal pain in one year after surgery in patients with a history of preoperative H. pylori, pylori can be a potential cause of postoperative chronic pain. https://acta.tums.ac.ir/index.php/acta/article/view/8768