Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 60 9 2022 11 08 Comparisons of Modulation Transform Function in 2 Monofocal Spherical Hydrophobic and Hydrophilic Intra Ocular Lenses 594 598 Tahereh Abdolahinia Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran Hassan Hashemi Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran Ebrahim Jafarzadehpur Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Abbasaali Yekta Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Mahshid Saffarpour Department of Restorative Dentistry, School of Dentistry, Alborz University of Medical Sciences, Tehran, Iran Abolfazl Jafarzadehpour Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran Effat Shanbezadeh Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran Mehdi Khabazkhoob Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2021 03 14 2022 06 09 To compare Modulation Transform Function (MTF) between standard monofocal spherical hydrophobic acrylic Alcon SA60AT (Bausch and Lomb) and hydrophilic acrylic Rayner Superflex (620H) (Rayner) intra-ocular lenses (IOLs). This cross-sectional study was conducted on 68 patients who underwent cataract surgery. The hydrophobic Alcon SA60AT IOL was implanted in 39, and the hydrophilic Rayner Superflex (620H) was implanted in 29 eyes. The OPD Scan III (Nidek) was used to assess MTF in normal pupils under mesopic light conditions 1 and 3 months after the surgery. t-test showed no significant difference in mean MTF between the two IOLs in the 2 follow-ups (P=0.788). The results of repeated measure ANOVA for each type of IOL indicated that MTF increased significantly in the hydrophilic group versus the hydrophobic group in the 3rd month (P=0.033). Moreover, the results of repeated measure ANOVA showed that MTF was affected by the type of IOL and refractive error in the 3rd month (P=0.029, P=0.025). It seems that the material of IOL and post-surgical residual refractive error can affect the visual acuity of pseudophakic patients. Although the hydrophilic IOL provided a better MTF three months after the surgery, studies with longer follow-ups are required to confirm the results. https://acta.tums.ac.ir/index.php/acta/article/view/9236