Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 60 9 2022 11 08 575 582 Alia Saberi Department of Neurology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Sajjad Saadat Neuroscience Research Center, Guilan University of Medical Sciences, Rasht, Iran. Ali Pourramazani Department of Psychiatry, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Fateme Eftekhari Clinical Research Development Unit of Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran Hamidreza Hatamian Department of Neurology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Marjan Entezari Department of Counseling, Ferdowsi University of Mashhad, Mashhad, Iran 2021 06 05 2021 11 17 The aim of this study was to evaluate the burnout, anxiety, and professional self-concept of nurses according to their demographic and occupational information. 160 nurses from Razi and Poursina hospitals in Iran were selected as a sample in this cross-sectional online survey and answered the tools Demographic and Occupational Information Questionnaire (DOIQ), Maslach Burnout Inventory-Human Services Survey (MBI-HSS), Corona Disease Anxiety Scale (CDAS) and Nurse Self-Concept Questionnaire (NSCQ). Data analysis was performed in two descriptive and inferential sections using SPSS-19 statistics software. The participation rate in this study was 87.5% (n=140). The mean age was 32.56 (SD=7.26) years. The burnout rate in emotional exhaustion (EE) was 24.3%, depersonalization (DP) was 32.1%, and personal accomplishment (PA) was 60.7%, 21.4% of nurses had high anxiety, and 53.6% had low NSCQ. EE score was higher in nurses with less than ten years of experience (t=2.21) and single people (t=-3.18). DP score was higher in people under 35 years (t=3.20), with work experience of fewer than ten years (t=4.34), and single people (t=-3.07). Females in PA reported more burnout (t=-2.43). CDAS score was higher in females (t=3.20). NSCQ score was higher in married people (t=-3.07). CDAS was positively correlated with EE and DP and negatively correlated with PA. NSCQ was negatively correlated with EE and DP and positively correlated with PA. At first, a high CDAS score and then celibacy, less than ten years of work experience, and a low NSCQ score were effective in multiple linear regression analysis for MBI-HSS. https://acta.tums.ac.ir/index.php/acta/article/view/9440