Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 277 282 A Nikzamir Department of Biochemistry, School of Medicine, Ahwaz Jondi Shapour University of Medical Sciences, M Nakhjavani Endocrinology and Metabolism Research Center (EMRC), Vali-e-Asr Hospital, Tehran University of Medic T Golmohammadi Department of Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran L Dibai Endocrinology and Metabolism Research Center (EMRC), Vali-e-Asr Hospital, Tehran University of Medic R Saffary Endocrinology and Metabolism Research Center (EMRC), Vali-e-Asr Hospital, Tehran University of Medic 2015 09 28 Diabetes mellitus is a multifactorial disease. It has recently been shown that an insertion (I)/deletion (D) polymorphism exists in the angiotensin-converting enzyme (ACE) gene that can affect the serum ACE level. There are three genotypes: DD, DI, and II, with the ACE level being highest in DD, intermediate in DI, and lowest in II. In the present investigation, 170 patients with type 2 diabetes mellitus (T2DM) and 144 control subjects were studied. The ACE I/D polymorphism was determined by polymerase chain reaction (PCR) utilizing specific primers. ACE activity was determined spectrophotometrically. Distribution of ACE gene (I/D) polymorphism and allele frequencies in patients with T2DM were significantly different from those in control (P < 0.001); D allele frequency was 51% in T2DM vs. 48% in controls. The level of ACE activity was significantly higher in the DD genotype (91.1 ± 23.18) than those in ID (60.6 ± 22.8) and in II genotypes (36.8 ± 6.9). There was a significant difference in genotype distribution between the two groups (P < 0.001). New normal ranges of serum ACE level were determined for each genotype. Moreover, we found test sensitivity to be 62.3%. Serum ACE activity was significantly associated with ACE (I/D) gene polymorphism. https://acta.tums.ac.ir/index.php/acta/article/view/3482 https://acta.tums.ac.ir/index.php/acta/article/download/3482/3459

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 283 286 V Rahimi-Movaghar Sina Trauma and Surgery Research Center, Sina Hospital, School of Medicine, Tehran University of Med A Yazdi Department of Neurosurgery, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Ira S Saadat Sina Trauma and Surgery Research Center, Sina Hospital, School of Medicine, Tehran University of Med 2015 09 28 The dysesthesia and paresthesia that occurs in laboratory rats after spinal cord injury (SCI) results in autophagia. This self-destructive behavior interferes with functional assessments in designed studies and jeopardizes the health of the injured rat. In this study, we evaluated role of saturated picric acid in the prevention of autophagia and self-mutilation. All rats were anesthetized with an intraperitoneal injection of a mixture of ketamine (100 mg/kg) and xylazine (10 mg/kg) for the SCI procedures. In the first 39 rats, no solution applied to the hind limbs, but in the next 26 cases, we smeared the saturated picric acid on the tail, lower extremities, pelvic, and abdomen of the rats immediately after SCI. In the rats without picric acid, 23 rats died following autophagia, but in the 26 rats with picric acid, there was no autophagia (P < 0.001). Picric acid side effects in skin and gastrointestinal signs such as irritation, redness and diarrhea were not seen in any rat. Saturated picric acid is a topical solution that if used appropriately and carefully, might be safe and effectively prevents autophagia and self-mutilation. When the solution is applied to the lower abdomen and limbs, we presume that its bitterness effectively prevents the rat from licking and biting the limb. https://acta.tums.ac.ir/index.php/acta/article/view/3483 https://acta.tums.ac.ir/index.php/acta/article/download/3483/3460

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 287 290 M. R Emamhadi Department of Neurosurgery, School of Medicine, Guilan University of Medical Sciences, Guilan, Iran H. R Hatamian Department of Neurology, School of Medicine, Guilan University of Medical Sciences, Guilan, Iran 2015 09 28 Pain, particularly after surgery, can create a variety of side effects including delay in wound healing. Different drugs such as pethidine and non-steroidal anti-inflammatory drugs are used for relieving patient's pain after surgery. The purpose of this research was to compare effect of pethidine vs. diclofenac (D) suppository in relief of pain after laminectomy. A total of 100 patients who underwent laminectomy entered this study. They were divided into pethidine and diclofenac groups. The patients' pain score was measured with visual analog scale (VAS) method. The mean pain score 24 hours after surgery was 2.8 ± 2.0 in pethidine group and 4.46 ± 2.30 in diclofenac group. There was a significant statistical difference between pain score after surgery in two groups (P < 0.05). Nausea was the most common side effect observed in pethidine group (20%) and epigastric pain was the most common one in diclofenac group (18%). There wasn't any statistical significant difference between side effects in these two groups. It seems that pethidine injection is more effective than diclofenac suppository in relieving pain after laminectomy. https://acta.tums.ac.ir/index.php/acta/article/view/3484 https://acta.tums.ac.ir/index.php/acta/article/download/3484/3461

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 291 294 A Davoodabadi Department of General and Thoracic Surgery, School of Medicine, Kashan University of Medical Science F Sadr Department of Internal Medicine, School of Medicine, Kashan University of Medical Sciences, Kashan, E Razi Department of Internal Medicine, School of Medicine, Kashan University of Medical Sciences, Kashan, H Adeli Department of Internal Medicine, School of Medicine, Qum University of Medical Sciences Qum, Iran 2015 09 28 Parapneunomonic effusion is a common accompaniment of bacterial pneumonia and mostly is resolved with medical management. We studied the etiology and possible underlying causes of complicated parapneumonic effusion and timing of pulmonary decortication. A descriptive study on 34 patients with postpneumonic empyema which required decortication carried out. Post surgical and post traumatic empyema were excluded. Patients' age ranged from 20 to 75 with a mean of 46 years. The most common clinical findings were fever (90%), pleural dull pain (80%), productive cough (73%) and dyspnea (70%). PPD test was negative in all patients. In 78%, white cell count was normal; in remainder it was more than 10.000. Bacteriological findings were negative and acid fast basili were not detected. All patients underwent posterolateral thoracotomy and decortication and completely expansible lung was achieved. Tissue diagnosis after decorticating showed tuberculosis in 8(24%) patients and necrotic tissue in remainder. Average medical management time and postoperative hospital stay were 38 ± 2 and 6.7 ± 2 days, respectively. Morbidity rates were acceptable and there was one late ortality. No recurrent was happened. In parapneumonic effusions not responding to standard treatment, tuberculosis must be considered, especially in addicted persons, positive family history and ESR >100. In complicated parapneumonic effusion, early thoracotomy and full decortication is recommend because it is diagnostic, allows control of infection, releases the pulmonary entrapment, early discharge from hospital, need not further antibiotic administration and is cost benefit. https://acta.tums.ac.ir/index.php/acta/article/view/3485 https://acta.tums.ac.ir/index.php/acta/article/download/3485/3462

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 295 298 R Zarei Associate Professor of Ophthalmology, Eye Research Center, Tehran University of Medical Sciences, Te S Shahhosseini Ophthalmologist G Faragee-Oskouee Associate Professor of Ophthalmology, Eye Research Center, Tehran University of Medical Sciences, Te A. R Shokoh Ophthalmologist K Hamzehdoost Assistant Professor of Ophthalmology, Eye Research Center, Tehran University of Medical Sciences, Te 2015 09 28 The most common cause of failure during the first trimester after trabeculectomy is encapsulated bleb and needling bleb revision is a less invasive method in the management of refractory cases. The purpose of this study is to determine the efficacy and safety of mitomycin-C (MMC) augmented bleb revision of failed filtration surgery. This study is a before-after (paired) observation. 33 patients with failed trabeculectomy because of bleb encapsulation, whose intraocular pressure (IOP) was not reduced under 21 mmHg despite of medications and digital massage , underwent needling bleb revision and subconjunctival injection of 0.1 ml MMC (0.4 mg/ml).The mean follow-up time was 9.24 ± 5.27 months (1-20 months). Statistical analysis of the data included the paired two-tailed Student's t test for preoperative and postoperative IOP and number of medications. 36 needling procedures (mean, 1.09 ± 0.21 revisions per eye) were performed on 33 eyes. Patients were between 10-80 years old (mean, 45.67 ± 22.41 years) and mean follow-up was 9.24 ± 5.27 months. IOP decreased from 29.06 ± 5.03 mmHg to 18.21 ± 6.76 mmHg at last follow-up (P= 0.000). Antiglaucoma medications decreased from 2.18 ± 0.58 to 1.36 ± 0.29 at last follow-up (P= 0.000).Overall, 6 (18.2%) of 33 cases achieved a complete success and 20 (60.6%) of cases achieved a qualified success. The complications of this procedure were subconjunctival hemorrhage (17 cases), hyphema (5 cases) and conjunctival button hole (2 cases). Needling bleb revision with mitomycin-C appears to be an effective and relatively safe way to revive failed filtration surgery. https://acta.tums.ac.ir/index.php/acta/article/view/3486 https://acta.tums.ac.ir/index.php/acta/article/download/3486/3463

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 299 302 P Akbari-Asbagh Department of Pediatric Cardiology, Imam Khomeini Hospital, School of Medicine, Tehran University of M. A Navabi Department of Pediatric Cardiosurgery, Imam Khomeini Hospital, School of Medicine, Tehran University 2015 09 28 Postoperative low cardiac output states are a major cause of postoperative mortality in infants and children following corrective cardiac surgery or congenital heart defects. Whole body hypothermia has been used since 2001 in the management of these low output states when they are refractory to conventional modes of therapy. From December 2001 to April 2006, 25 cases were included in this study. The median (range) age of patients was 36.6 months (1 mo-19 y) with a median weight of 12.2 kg (3.5-44 kg). Following cooling, there was a decrease in heart rate (P< 0.001), an increase in mean arterial pressure (P< 0.001) and a decrease in mean arterial pressure (P< 0.001). Significant increases in pH and urine output were also noticed, the increase in urine output being greater in the surviving group (P= 0.02). A decrease in platelet count was occurred (P https://acta.tums.ac.ir/index.php/acta/article/view/3487 https://acta.tums.ac.ir/index.php/acta/article/download/3487/3464

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 303 306 F Ashtari Department of Neurology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran V Shayegannejad Department of Neurology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran A Saberi Department of Neurology, School of Medicine, Guilan University of Medical Science, Guilan, Iran E Rabiee General Practitioner, Isfahan, Iran 2015 09 28 Several studies have assessed association between Helicobacter pylori infection and thrombotic ischemic stroke. This study was designed to investigate the association between this organism and ischemic strokes. Antibody against H. pylori (Hp IgG) was measured in 81 patients with stroke and 43 subjects without stroke. Hp IgG titer more than 20u/ml was defined as positive. 67.4% of control subjects and 70.4% of cases were Hp IgG seropositive (P = 0.838). The means of serum Hp IgG titers in control subjects and cases were 51.1859 u/ml and 50.1641 u/ml, respectively (P = 0.927). The difference between these 2 groups was not significant statistically. There wasn't any significant difference in seropositivity of Hp IgG between case and control subjects in men and women. H. pylori IgG titer hasn't a predictive role for thrombotic ischemic stroke. https://acta.tums.ac.ir/index.php/acta/article/view/3488 https://acta.tums.ac.ir/index.php/acta/article/download/3488/3465

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 46 4 2008 08 15 307 313 A Khademi Sport Medicine Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, I L Tabatabaeefar Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran E Akbari Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran A Alleyassin Department of Obstetrics and Gynecology, School of Medicine, Tehran University of Medical Sciences, V Ziaee Sport Medicine Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, I A Asghari-Roodsari Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2015 09 28 A number of studies have examined the role of aerobic exercise and evidence suggests this may be an effective therapy for premenstrual syndrome (PMS). The aim of this study was to assess the PMS symptoms between swimmer and non-swimmer female students. Two hundred eighty subjects were studied. One hundred forty subjects were swimmers, while 140 were normal sedentary controls. Duration of swimming per week, and the length of exercise were asked from the case group. The predominant symptom of PMS was determined. PMS occurred in 36.2% and 22.8% of non-swimmers and swimmers Department of Paediatric Infectious Diseases , Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Peyman Salamati Department of Community Medicine, Tehran University of Medical Sciences, Tehran, Iran. Mohammadreza Ashrafi Department of Pediatric Neurology, Children Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Manelie Sadeghi Specialist in Community Medicine, Research Development Center, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Javad Tavakoli Department of Pediatric, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Febrile convulsion (FC) is the most common seizure disorder in childhood. white blood cell (WBC) and erythrocyte sedimentation rate (ESR) are commonly measured in FC. Trauma, vomiting and bleeding can also lead to WBC and ESR so the blood tests must carefully be interpreted by the clinician. In this cross sectional study 410 children(163 with FC), aged 6 months to 5 years, admitted to Bahrami Children hospital in the first 48 hours of their febrile disease, either with or without seizure, were evaluated over an 18 months period. Age, sex, temperature; history of vomiting, bleeding or trauma; WBC, ESR and hemoglobin were recorded in all children. There was a significant increase of WBC (P<0.001) in children with FC so we can deduct that leukocytosis encountered in children with FC can be due to convulsion in itself. There was no significant difference regarding ESR (P=0.113) between the two groups. In fact, elevated ESR is a result of underlying pathology. In stable patients who don't have any indication of lumbar puncture, there's no need to assess WBC and ESR as an indicator of underlying infection. If the patient is transferred to pediatric ward and still there's no reason to suspect a bacterial infection, there is no need for WBC test. https://acta.tums.ac.ir/index.php/acta/article/view/3773 https://acta.tums.ac.ir/index.php/acta/article/download/3773/3748

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 451 455 EN Mostafa Hosseini Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Seyed Meisam Ebrahimi Faculty of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. SeyedAhmad SeyedAlinaghi Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. Mahmood Mahmoodi Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 We assessed the lower urinary tract symptoms (LUTS) in prostatic cancer patients and investigated the sensitivity and specificity of international prostate symptom score (IPSS) in the screening of these patients. A total number of 132 prostatic cancer patients as the case group who were confirmed by the pathologists and 101 noncancerous men as the control group, aged 50 or older, responded to a questionnaire which included seven questions regarding urination, named the International Prostate Symptom Score (IPSS). Then, two groups were assessed and compared with each other and also the sensitivity and specificity of IPSS tool for screening of prostatic cancer patients were calculated. All participants filled out the questionnaire. 60 (59.4%) noncancerous men and 29 (22.0%) cases had mild LUTS, and 41 (40.6%) noncancerous men and 103 (78.0%) cases had moderate to severe LUTS. Moreover, the sensitivity and specificity of the IPSS tool were 78% and 59.4%, respectively. Urination status and problems could be easily assessed by IPSS and it is a sensitive and specific tool for screening of prostatic cancer patients. It appears that IPSS is a cost beneficial, sensitive, specific and easily-used screening tool to diagnose the prostate cancer cases. Therefore, it can be used more extensively by the health care providers as well as by men ≥50 years old themselves. https://acta.tums.ac.ir/index.php/acta/article/view/3774 https://acta.tums.ac.ir/index.php/acta/article/download/3774/3749

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 456 459 EN Seyed Mohammad Godsi Department of Neurosurgery, Tehran University of Medical Science, Tehran, Iran. Asadollah Saadatniaki Department of Anesthesiology, Shahid Beheshti University of Medical Science, Tehran, Iran. Mir Moussa Aghdashi Department of Anesthesiology & Pain Medicine Fellow, Urmia University of Medical Science, Urmia, Iran. Nayereh Khodashenas Firoozabadi Department of Anesthesiology, Khatamolanbiya General Hospital, Pain Clinic Director. Payam Dadkhah Department of Anesthesiology & Pain Medicine Fellow, Shahid Beheshti University of Medical Science, Tehran, Iran. 2015 09 28 Among patients with chronic unrelieved pain, war veterans of eight years long Iraq - Iran war deserve especial attention. They not only suffer from severe intractable pain but also should bear some intangible consequences of unrelieved pain and severe disability. This perspective study reviews the outcome of implantation of intrathecal opioid pumps in these patients. Ten war veterans (mean age 43.36) with chronic nonmalignant pain included in this perspective study. Medical records reviewed to identify pain diagnosis, medication intake prior to implantation, details of the intrathecal opioid trial and date of implantation, surgical and technical complications. Outcome measures were global pain relief, physical activity levels, intrathecal opioid side effects, medication consumption and patient satisfaction. Overall pain relief at the time of study was 60%. Mean pain relief was 53%. A majority of patients reported improvements in physical activity levels and were satisfied with this type of therapy. Impotence and constipation were two most common pharmacological side effects. No surgical complication reported. The study showed that this type of therapy in Iranian war veterans improved analgesia, increased self-report physical activity levels and in spite of high incidence of pharmacological side effects, most of the patients were satisfied with this type of therapy. These results are comparable to those of previous studies in this field. https://acta.tums.ac.ir/index.php/acta/article/view/3775 https://acta.tums.ac.ir/index.php/acta/article/download/3775/3750

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 460 467 EN Banafsheh Moradmand Badie Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Tahereh Soori Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Parastoo Kheirandish Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Saeed Izadyar Department of Nuclear Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. SeyedAhmad SeyedAlinaghi Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Maryam Foroughi Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. Alireza Rostamian Department of Rheumatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Minoo Mohraz Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Bone disorders have emerged as a worrisome complication in HIV-infected patients in recent years. It is not clear that HIV infection itself or antiretroviral treatment or both are causes of bone loss. However, most studies have found a high prevalence of osteopenia and osteoporosis in HIV/AIDS patients. The objectives of this study were to determine the prevalence of osteopenia and osteoporosis in HIV-infected patients either untreated or receiving Highly Active Antiretroviral Therapy as compared with HIV negative persons. We also assessed the factors associated with these conditions. Bone Mineral Density was assessed by Dual Energy X-Ray Absorptiometry scans at the hip and lumbar spine in 36 AIDS patients receiving antiretroviral therapy and 44 HIV infected patients not receiving antiretroviral therapy (naïve patients) and 40 HIV negative individuals as control. Factors that affect BMD were also determined. Prevalence of osteopenia or osteoporosis in different regions was significantly higher in HIV/AIDS patients compared with HIV negative subjects (77.3% in HIV positive naïve patients, 86.1% in HAART-treated patients and 60% in the control group, P=0.002). Mean serum alkaline phosphatase was higher in HIV/AIDS patients than the control group (P=0.003). Osteopenia and osteoporosis in HIV-infected patients were associated with duration of HIV infection (P<0.0001) and antiretroviral treatment (P=0.012). Prevalence of osteopenia and osteoporosis in HIV/AIDS patients was higher than HIV negative individuals. Osteopenia and osteoporosis in HIV/AIDS patients was associated with duration of HIV infection and antiretroviral treatment. https://acta.tums.ac.ir/index.php/acta/article/view/3776 https://acta.tums.ac.ir/index.php/acta/article/download/3776/3751

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 468 471 EN Katayoon Bidad Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. AND Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Shahab Anari Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Sanaz Tavasoli Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran. AND Department of Nutrition, Faculty of Health, Tehran University of Medical Sciences, Tehran, Iran. Leili Nazemi Department of Nutrition, Faculty of Health, Tehran University of Medical Sciences, Tehran, Iran. Heshmat Moayeri Department of Pediatric Endocrinology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Dietary factors are suggested to be involved in recent increases in the prevalence of asthma. The differences in dietary intake of 23 asthmatic and 317 non-asthmatic students were investigated, who were chosen by multistage stratified cluster sampling. The dietary data were assessed by food frequency questionnaire and a 24-h recall form. Total calorie and fat intake were similar. Daily intake of Saturated and poly-unsaturated fatty acids, and calcium and sodium were significantly higher in asthmatics. There was no significant difference between dietary antioxidant intake of asthmatic and non asthmatics. It seems that in this age, the type of consumed fat may be more important than the amount of fat intake in inducing asthma. For accurate results, n-6 and n-3 fatty acid intake must be assessed. Higher sodium and calcium intake may also be associated with asthma. Randomized controlled trials with restricting diets can help to elucidate the results. https://acta.tums.ac.ir/index.php/acta/article/view/3777 https://acta.tums.ac.ir/index.php/acta/article/download/3777/3752

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 472 477 EN Reza Nemati Ahmadabad Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. Hayede Ghaninezhad Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. Homayoon Moslehi Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. Sahar Azizahari Department of Dermatology, Research Development Centre of Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. Kambiz Kamyab Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. Azita Nikoo Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2015 09 28 Proper differentiation between acral malignant melanoma and benign pigmented lesions like melanocytic nevi is of great value. To avoid unnecessary biopsies, dermatoscopy has been introduced as a non-invasive modality and has improved the clinical diagnostic accuracy in recent decades. We aimed to describe dermoscopic patterns of acral pigmented lesions of patients in the clinic of dermatology in Razi Hospital, Tehran, Iran. This study was conducted as a descriptional study among a total of 62 pigmented lesions located on volar skin of palms and soles. After initial clinical evaluation, lesions were examined entirely by dermoscopy. All the patterns within a lesion were described, and lesions suspicious of malignancy (clinically or dermatoscopically) were selected for histopathological evaluation. Of our 62 lesions, three lesions were not melanocytic. According to our final clinicopathological diagnosis, 47 lesions were benign melanocytic nevi and 12 lesions were malignant melanoma. Parallel furrow pattern was the most frequent among our benign lesions (51.1%) followed by lattice-like pattern (23.4%) and acral reticular pattern (21.3%). Diffuse multi-component pattern, parallel ridge pattern and abrupt edge were respectively most common patterns among malignant melanomas. Acral benign melanocytic nevi and malignant melanomas respectively have well distinctive characteristics in dermatoscopy among our patients. https://acta.tums.ac.ir/index.php/acta/article/view/3778 https://acta.tums.ac.ir/index.php/acta/article/download/3778/3753

Tehran University of Medical Sciences Acta Medica Iranica 0044-6025 49 7 2011 07 15 478 479 EN Hossain Jabbari Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Amir Houshang Sharifi Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. SeyedAhmad SeyedAlinagh Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Parastoo Kheirandish Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Abbas Sedaghat Ministry of Health and Medical Education, Tehran, Iran. Maryam Sargolzaei Ministry of Health and Medical ducation, Tehran, Iran. Gholamreza Esmaeeli Djavid Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Ahmad Khanbabae Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mehrnaz Rasoolinejad Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Minoo Mohraz Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Willi McFarland CAPS and the Institute for Global Health, University of California, San Francisco, USA. 2015 09 28 Throughout the world, many migrant and mobile populations are at elevated risk for HIV. Iran has a large immigrant population from neighboring Afghanistan; however, few data exist on the prevalence of HIV in this community. In 2008, we conducted a study to assess the presence of HIV infection among 477 immigrants in a town to the northeast of Tehran using a rapid test in the field. HIV prevalence was 0.2% (95% CI 0.005-1.2) with one person HIV-positive. We recom