Relationship between Oral Poor Hygiene and Broken Teeth with Oral Tongue Squamous Cell Carcinoma

  • Fatholah Behnoud Department of ENT, Besat Hospital, School of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran.
  • Saadat Torabian Department of ENT, Besat Hospital, School of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran.
  • Maasoumeh Zargaran Faculty of Dentistry, Hamedan University of Medical Sciences, Hamedan, Iran.
Keywords: Oral tongue, Squamous cell carcinoma, Oral hygiene, Broken tooth

Abstract

Previous studies on etiology of squamous cell carcinoma (SCC) of the tongue have reported results with respect to long term exposure to cigarette smoking and alcohol abuse. The aim of this study was to investigate risk factors for SCC of the tongue in a set of patients with minimum exposure to cigarette smoking and alcohol. Sixty four cases with diagnosis of oral tongue SCC were reviewed in this study. The patients underwent surgical management at the educational and therapeutic centers, Imam and Buali Hospitals (Hamedan, Iran) between the dates of January 1990 and December 2006. Eighty five percent of patients were older than 40 years of age. Most of patients had poor oral hygiene, dental decay and halitosis. It appears that poor oral hygiene and nutritional deficiency can be considered as risk factors for the SCC of the tongue in west of Iran.

References

Garavello W, Spreafico R, Gaini RM. Oral tongue cancer in young patients: a matched analysis. Oral Oncol 2007;43(9):894-7.

Huang X, Wei Y, Li L, Wen Y, Yang J, Liu B, Song X, Zhao J. Serum proteomics study of the squamous cellcarcinoma antigen 1 in tongue cancer. Oral Oncol 2006;42(1):26-31.

Yazici YD, Kim S, Jasser SA, Wang Z, Carter KB Jr, Bucana CD, Myers JN. Antivascular therapy of oral tongue squamous cell carcinoma with PTK787. Laryngoscope 2005;115(12):2249-55.

Llewellyn CD, Linklater K, Bell J, Johnson NW, Warnakulasuriya S. An analysis of risk factors for oralmcancer in young people: a case-control study. Oral Oncol2004;40(3):304-13.

Ernster JA, Sciotto CG, O'Brien MM, Finch JL, RobinsonLJ, Willson T, Mathews M. Rising incidence oforopharyngeal cancer and the role of oncogenic human papilloma virus. Laryngoscope 2007;117(12):2115-28.

Stoeckli SJ. Sentinel node biopsy for oral and oropharyngeal squamous cell carcinoma of the head and neck. Laryngoscope 2007;117(9):1539-51.

Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for oral cancer in newly diagnosed patients aged 45 years and younger: a case-control study in Southern England. J Oral Pathol Med 2004;33(9):525-32.

Papageorge MB. Etiology of oral cancer in the young patient: is tongue cancer becoming the other cancer in women? Oral Maxillofac Surg Clin North Am 2007;19(2):163-71.

de Vicente JC, Olay S, Lequerica-Fernandez P, Sánchez- Mayoral J, Junquera LM, Fresno MF. Expression of Bcl-2 but not Bax has a prognostic significance in tongue carcinoma. J Oral Pathol Med 2006;35(3):140-5.

Lim YC, Lee JS, Koo BS, Kim SH, Kim YH, Choi EC. Treatment of contralateral N0 neck in early squamous cell carcinoma of the oral tongue: elective neck dissection versus observation. Laryngoscope 2006;116(3):461-5.

Davies L, Welch HG. Epidemiology of head and neck cancer in the United States. Otolaryngol Head Neck Surg 2006;135(3):451-7.

Velly AM, Franco EL, Schlecht N, Pintos J, Kowalski LP,Oliveira BV, Curado MP. Relationship between dental factors and risk of upper aerodigestive tract cancer. Oral Oncol 1998;34(4):284-91.

Anil S, Al-Ghamdi HS. The impact of periodontal infections on systemic diseases. An update for medical practitioners. Saudi Med J 2006;27(6):767-76.

Liao CT, Wang HM, Hsieh LL, Chang JT, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Kang CJ, Huang SF, Yen TC. Higher distant failure in young age tongue cancer patients. Oral Oncol 2006;42(7):718-25.

Menezes MB, Lehn CN, Gonçalves AJ. Epidemiologicaland histopathological data and E-cadherin-like prognostic factors in early carcinomas of the tongue and floor of mouth. Oral Oncol 2007;43(7):656-61.

Moreno-López LA, Esparza-Gómez GC, González- Navarro A, Cerero-Lapiedra R, González-Hernández MJ, Domínguez-Rojas V. Risk of oral cancer associated with tobacco smoking, alcohol consumption and oral hygiene: amcase-control study in Madrid, Spain. Oral Oncol 2000;36(2):170-4.

Keski-Säntti H, Atula T, Tikka J, Hollmén J, Mäkitie AA, Leivo I. Predictive value of histopathologic parameters in early squamous cell carcinoma of oral tongue. Oral Oncol 2007;43(10):1007-13.

Lazarchik DA, Filler SJ. Dental erosion: predominant oral lesion in gastroesophageal reflux disease. Am J Gastroenterol 2000;95(8 Suppl):S33-8.

Yang KY, Jiang RS, Shiao JY, Wang CC, Wang CP, Liang KL, Twu CW, Liu SA. Visual screening of oral cavity cancer: The role of otolaryngologists. Laryngoscope 2007;117(1):92-5.

How to Cite
1.
Behnoud F, Torabian S, Zargaran M. Relationship between Oral Poor Hygiene and Broken Teeth with Oral Tongue Squamous Cell Carcinoma. Acta Med Iran. 49(3):159-162.
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