Simultaneous Shoulder and Hip Dislocation in a 12-Year-Old Girl with Hutchinson-Gilford Progeria Syndrome
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Abstract
Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems. Mean age at diagnosis is 2.9 years and generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. Orthopedic manifestations of HGPS are multiple and shoulder dislocation is a rare skeletal trauma in progeria syndrome. Our patient had simultaneous shoulder and hip dislocation associated with a low energy trauma. This subject has not been reported. Treatment accomplished as close reduction under general anesthesia and immobilization.
Pereira S, Bourgeois P, Navarro C, Esteves-Vieira V, Cau P, De Sandre-Giovannoli A, Lévy N. HGPS and related premature aging disorders: from genomic identification to the first therapeutic approaches. Mech Ageing Dev 2008;129(7-8):449-59.
Ackerman J, Gilbert-Barness E. Hutchinson-Gilford progeria syndrome: a pathologic study. Pediatr Pathol MolMed 2002;21(1):1-13.
Shah KN, Elston DM. Hutchinson-Gilford Progeria. [Internet] 2011 Sep 8 [cited 2012 May 15]; Available from: http://emedicine.medscape.com/article/1117344- overview
Hogan PA, Krafchik BR. Hutchinson-Gilford syndrome.Pediatr Dermatol 1990;7(4):317-9.
Hennekam RC. Hutchinson-Gilford progeria syndrome: review of the phenotype. Am J Med Genet A 2006;140(23):2603-24.
Pollex RL, Hegele RA. Hutchinson-Gilford progeria syndrome. Clin Genet 2004;66(5):375-81.
Nakamura S, Makita Y, Takagi A, Hashimoto Y, Takahashi H, Ishida-Yamamoto A, Iizuka H. Hutchinson- Gilford progeria syndrome with severe skin calcinosis. Clin Exp Dermatol 2007;32(5):525-8.
Sarkar PK, Shinton RA. Hutchinson-Guilford progeria syndrome. Postgrad Med J 2001;77(907):312-7.
Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB, Brewer CC, Zalewski C, Kim HJ, SolomonB, Brooks BP, Gerber LH, Turner ML, Domingo DL, Hart TC, et al. Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med 2008;358(6):592-604.
Maloney WJ. Hutchinson-Gilford Progeria syndrome: its presentation in F. Scott Fitzgerald's short story 'The Curious Case of Benjamin Button' and its oral manifestations. J Dent Res 2009;88(10):873-6.
Kieran MW, Gordon L, Kleinman M. New approaches toprogeria. Pediatrics 2007;120(4):834-41.
Moen C. Orthopaedic aspects of progeria. J Bone Joint Surg Am 1982;64(4):542-6.
Jackson WP. Osteoporosis of unknown cause in younger people: idiopathic osteoporosis. J Bone Joint Surg Br 1958;40-B(3):420-41.
Badame AJ. Progeria. Arch Dermatol 1989;125(4):540-4.
Thomson J, Forfar JO. Progeria (Hutchinson-Gilford Syndrome). Arch Dis Child 1950;25(123):224-34.
Mazereeuw-Hautier J, Wilson LC, Mohammed S, Smallwood D, Shackleton S, Atherton DJ, Harper JI. Hutchinson-Gilford progeria syndrome: clinical findings in three patients carrying the G608G mutation in LMNA and review of the literature. Br J Dermatol 2007;156(6):1308-14.
Ramesh V, Jain RK. Progeria in two brothers. Australas J Dermatol 1987;28(1):33-5.
Ozonoff MB, Clemett AR. Progressive osteolysis in progeria. Am J Roentgenol Radium Ther Nucl Med 1967;100(1):75-9.
de Paula Rodrigues GH, das Eiras Tâmega I, Duque G, Spinola Dias Neto V. Severe bone changes in a case of Hutchinson-Gilford syndrome. Ann Genet 2002;45(3):151-5.
Daniels SR. The biology of progeria syndrome. J Pediatr 2005;146(3):A2.
Korf B. Hutchinson-Gilford progeria syndrome, aging, and the nuclear lamina. N Engl J Med 2008;358(6):552-5.
Ershler WB, Ferrucci L, Longo DL. Hutchinson-Gilford progeria syndrome. N Engl J Med 2008;358:2409-10.
Halaschek-Wiener J, Brooks-Wilson A. Progeria of stem cells: stem cell exhaustion in Hutchinson-Gilford progeria syndrome. J Gerontol A Biol Sci Med Sci 2007;62(1):3-8.
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| Issue | Vol 50, No 6 (2012) | |
| Section | Articles | |
| Keywords | ||
| Accelerated aging Hutchinson-Gilford progeria syndrome | ||
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