Acta Medica Iranica 2013. 51(12):861-863.

Can preoperative serum level of creatinine predict new-onset atrial fibrillation in non-diabetic male patients undergoing open heart surgery? A retrograde view.
Seyed Jalil Mirhosseini, Sadegh Ali-Hassan-Sayegh, Ali Akbar Karimi-Bondarabadi, Mohammad Reza Mozayan

Abstract


Renal dysfunction is a risk marker in patients who candidate for coronary artery bypass graft (CABG). Renal disorder is associated with prolonged stays in intensive care unit and hospital, morbidity and mortality. Aim of this study is specific evaluation of association between preoperative creatinine (Cr) with atrial fibrillation (AF) after elective off-pump CABG in non-diabetic male patients with normal ejection fraction. Two hundred non-diabetic male patients with normal ejection fraction undergoing elective off pump CABG surgery enrolled in this cross-sectional study and were stratified by present or absence of postoperative atrial fibrillation: patients with postoperative new-onset atrial fibrillation (n=100) as group 1 and patients without new-onset postoperative atrial fibrillation as group 2 (n=100). Preoperative serological test of the participants, such as serum creatinine, were recorded in their medical dossiers. Data were analyzed in SPSS-16 software and tested for association between atrial fibrillation with creatinine level by using student t test, chi-square test or logistic regression. Cr level in patients with and without AF three days before surgery were 1.8±0.3 and 1.0±0.4 respectively (P value for Cr=0.00). On surgical day, mean Cr level in patients with and without AF were 1.6±0.2 and 1.1±0.5 respectively (P value for Cr = 0.00). Of the 100, male patients with postoperative AF, duration and frequency of recurrence of AF were not associated with Cr at three days before surgery and on surgical days (P>0.05). Patients with postoperative AF had unsuitable status of renal function compare to patients without AF; however, preoperative serum creatinine cannot associate with duration and frequency of recurrence of AF.

Keywords


Renal function; Atrial fibrillation; Elective off-pump CABG; Serum creatinine level

Full Text:

PDF

References


Lok CE, Austin PC, Wang H, Tu JV. Impact of renal insufficiency on short- and long-term outcomes afterncardiac surgery. Am Heart J 2004;148(3):430-8.

Howell NJ, Keogh BE, Bonser RS, Graham TR, Mascaro J, Rooney SJ, Wilson IC, Pagano D. Mild renal dysfunction predicts in-hospital mortality and postdischarge survival following cardiac surgery. Eur J Cardiothorac Surg 2008;34(2):390-5.

Reber D, Fritz M, Germing A, Marks P, Laczkovics A. mEarly outcome after off-pump coronary artery bypass grafting: effect on mortality and stroke. Rev Bras Cir Cardiovasc 2008;23(1):23-8.

Helgadottir S, Sigurdsson MI, Ingvarsdottir IL, Arnar DO, Gudbjartsson T. Atrial fibrillation following cardiac surgery: risk analysis and long- term survival. J Cardiothorac Surg 2012;7:87.

Karaca M, Demirbas MI, Biceroglu S, Cevik A, Cetin Y, Arpaz M, Yilmaz H. Prediction of early postoperative atrial fibrillation after cardiac surgery: is it possible? Cardiovasc J Afr 2012;23(1):34-6.

Jyrala A, Weiss RE, Jeffries RA, Kay GL. Effect of mild renal dysfunction (s-crea 1.2-2.2 mg/dl) on presentation characteristics and short- and long-term outcomes of onpump cardiac surgery patients. Interact Cardiovasc Thorac Surg 2010;10(5):777-82.

Radmehr H, Forouzannia SK, Bakhshandeh AR, Sanatkar M. Relation between preoperative mild increased in serum creatinine level and early outcomes after coronary artery bypass grafting. Acta Med Iran 2011;49(2):89-92.

Zakeri R, Freemantle N, Barnett V, Lipkin GW, Bonser RS, Graham TR, Rooney SJ, Wilson IC, Cramb R, Keogh BE, Pagano D. Relation between mild renal dysfunction and outcomes after coronary artery bypass grafting. Circulation 2005;112(9 Suppl):I270-5.

Takahashi Y, Takahashi A, Kuwahara T, Okubo K, Fujino T, Takagi K, Nakashima E, Kamiishi T, Hikita H, Hirao K, Isobe M. Renal function after catheter ablation of atrial fibrillation. Circulation 2011;124(22):2380-7.


Refbacks

  • There are currently no refbacks.


Creative Commons Attribution-NonCommercial 3.0

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.