Retinitis due to opportunistic infections in Iranian HIV infected patients.

  • Ali Abdollahi Department of Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Minoo Mohraz Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Mehrnaz Rasoulinejad Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Mona Shariati Department of Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Parastou Kheirandish Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Maryam Abdollahi Department of Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Tahereh Soori Department of Infectious Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Keywords: CMV, HIV/AIDS, Opportunistic infections, Retinitis, Toxoplasmosis, Tuberculosis

Abstract

We tried to evaluate prevalence and characteristics of Iranian HIV infected patients with retinitis due to opportunistic infections. In this cross sectional study, we evaluated 106 HIV infected patients via indirect ophthalmoscopy and slit lamp examination by 90 lens to find retinitis cases. General information and results of ophthalmologic examination were analyzed. Prevalence of retinitis due to opportunistic infections was 6.6%: cytomegalovirus (CMV) retinitis 1.88%, toxoplasmosis retinochoroiditis 1.88% and tuberculosis chorioretinitis 2.83%. CD4 count was higher than 50 cell/µlit in both cases with CMV retinitis. Along with increasing survival in the HIV infected patients, the prevalence of complications such as ocular manifestation due to opportunistic infections are increasing and must be more considered.

References

Moraes Jr HV. Ocular manifestations of HIV/AIDS. Curr Opin Ophthalmol 2002;13(6):397.

Vrabec TR. Posterior segment manifestations of HIV/AIDS* 1. Survey of ophthalmology 2004;49(2):131-57.

Banker AS, Chauhan R, Banker DA. HIV and opportunistic eye diseases. Expert Rev Ophthalmol 2009;4(2):173-85.

Goldberg DE, Smithen LM, Angelilli A, Freeman WR. HIV-associated retinopathy in the HAART era. Retina 2005;25(5):633.

Abdollahi A, MalekMadani MH, Zarei R, Sangesari T, Shirzadi AR, Abdollahi M. Ocular Manifestations in Patients Infected with Human Immunodeficiency Virus. Iran J Ophthalmol 2009;21(3):44-8.

Assefa Y, Yohannes A, Melesi A. Ocular manisestations of HIV/AIDS patients in Gondar University Hospital, Northwest Ethiopia. Ethio J Health Dev 2009;20(3).

Pathai S, Deshpande A, Gilbert C, Lawn SD. Prevalence of HIV-associated ophthalmic disease among patients enrolling for antiretroviral treatment in India: A crosssectional study. BMC Infect Dis 2009;9(1):158.

Gharai S, Venkatesh P, Garg S, Sharma S, Vohra R. Ophthalmic manifestations of HIV infections in India in the era of HAART: analysis of 100 consecutive patients evaluated at a tertiary eye care center in India. OphthalmicEpidemiol 2008;15(4):264-71.

Ayena K, Amedome K, Agbo A, Kpetessou-Ayivon A, Dzidzinyo B, Djagnikpo P, Banla M, Balo KP. Ocular manifestations in HIV/AIDS patients undergoing highly= active antiretroviral treatment (HAART) in Togo. Médecine tropicale: revue du Corps de santé colonial 2010;70(2):137.

Emina MO, Odjimogho SE. Ocular Problems in HIV and AIDS Patients in Nigeria. Optom Vis Sci 2010;87(12):979.

Otiti-Sengeri J, Colebunders R, Kempen JH, Ronald A, Sande M, Katabira E. The prevalence and causes of visual loss among HIV-infected individuals in Uganda. JAIDS 2010;53(1):95.

Lamichhane G, Shah D, Sharma S, Chaudhary M. Ocular manifestations in HIV/AIDS cases in Nepal. Nepal J Ophthalmol 2010;2(1):45-50.

Wiegand TWM, Young LHY. Cytomegalovirus Retinitis. Int Ophthalmol Clin 2006;46(2):91-110.

Commodaro AG, Belfort RN, Rizzo LV, Muccioli C, Silveira C, Burnier Jr MN, Belfor Jr R. Oculartoxoplasmosis: an update and review of the literature. Memórias do Instituto Oswaldo Cruz 2009;104(2):345-50.

Shukla D, Rathinam SR , Cunningham Jr ET . Contribution of HIV/AIDS to Global Blindness. Int Ophthalmol Clin 2007;47(3):27-43.

Gupta A, Gupta V. Tubercular posterior uveitis. Int Ophthalmol Clin. 2005;45(2):71.

Abdollahi A , Heidari-Bateni G , Zaeri R, Kheirandish P , Malekmadani MH, Mohraz M ,Abdollahi M , Rajabi MT. Clinical spectrum of 15 patients with HIV-related ocular involvement in Tehran . Int J Ophthalmol 2010; 3(4):331-6.

How to Cite
1.
Abdollahi A, Mohraz M, Rasoulinejad M, Shariati M, Kheirandish P, Abdollahi M, Soori T. Retinitis due to opportunistic infections in Iranian HIV infected patients. Acta Med Iran. 51(10):711-714.
Section
Articles